Information regarding Medical Examinations

Kyono ART Clinic Takanawa is an infertility treatment facility specializing in assisted reproductive technology (ART).
Information regarding medical examinations available at this clinic.

Information regarding Medical Examinations

Definition of Infertility

Failure to achieve pregnancy within two years or more, despite having normal conjugal relations.

Desired timing to start treatment

  • Wife younger than 35 years old: Failure to achieve pregnancy within 1 year.
  • Wife older than 35 years old: Failure to achieve pregnancy within 6 months.

Cause of Infertility

  • Fallopian tube factors → tube blockage, stenosis, adhesion.
  • Ovarian factors → PCOS (polycystic ovary syndrome), other ovulation disorders
  • Uterine factors → endometrial polyp, uterine submucous myoma, endometriosis
  • Azoospermia (obstructive azoospermia, non-obstructive azoospermia)
  • Spermatic varicocele
  • Erectile dysfunction, ejaculation disorder
  • Pituitary hypogonadism

Immunological infertility and other problems are considered to be causes of infertility.

Infertility is not only caused by female factors. 30-40% of all infertility cases are due to male factors, and 20% of all cases are due to both male and female factors. From this, cause of infertility is almost 50-50.

Male infertility

Medical Interview and Examination

Seminal examination, palpation and visual inspection, ultrasound examination and hormone test. Chromosomal test, AZF test, as needed.

Diagnosis and Treatment

Micro-TESE, Simple-TESE, spermatic vericocele (basically, one day surgery under local anesthesia is performed)

  1. 1.Azoospermia
    1. Non-obstructive azoospermia→Micro-TESE
    2. Obstructive azoospermia→ Simple-TESE, vasovasostomy
  2. Spermatic varicolele→ Low ligation
  3. Erectile dysfunction and ejaculation disorder → Counseling, drug administration (Viagra, Levitra, Cialis)
  4. Pituitary hypogonadism → hCG-rFSH therapy
  5. Other → Non-hormonal therapy (Chinese herbal remedy, vitamins, supplements, etc.), hormonal therapy (clomiphene, letrozole, etc.), AIH (mild oligozoospermia/asthenozoospermia, post-coital test), ICSI (severe oligozoospermia, asthenozoospermia, immotile sperm, azoospermia, conception failure due to in-vitro fertilization, etc.)

Female infertility

Medical interview, pelvic examination, hormone test, AMH, hysterosalpingography (HSG), basal body temperature, post-coital test, cervical mucosa, antisperm antibody, hysteroscopy, chlamydia test, cancer screening, etc.

  • Fallopian tubal factors → FT (Falloposcopic Tuboplasty), in-vitro fertilization
  • Ovarian factors → For PCOS, rFSH low dose step-up protocol, IVM (in-vitro maturation of inmature eggs), in-vitro fertilization
  • Uterine factors → Endometrial polyp, uterine submucous myoma → Resection
  • Endometriosis → Different methods depending on the age of the patient and duration of infertility
  • Unknown causes (immunological infertility) → in-vitro fertilization.

When the cause of infertility is unknown, combination treatment of in-vitro fertilization and micro fertilization may be implemented. For globozoospermia, or when fertilization rate by ICSI is less than 30%, combination treatment of ICSI and oocyte activation (Ca ionophore and strontium) may be implemented.


Kyono ART Clinic Takanawa
Kyono ART Clinic Takanawa
108-0074 3-13-1 Takanawa, Minato-ku, Tokyo, TAKANAWA COURT 5F [MAP]
TEL.+81-3-6408-4124 / FAX.+81-3-6408-4125
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Medical Consultation Hours
Monday, Tuesday (morning only), Wednesday, Thursday, Friday, Saturday
7:30-12:00 Last reservation 11:30 / 14:00-17:00 Last reservation 16:00
Sunday (Every other week) 9:00-14:00 Last reservation 13:30

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